Thursday 9 June 2011

MCQ 20

Which of the following is the drug of choice for the treatment of inappropriate anti-diuretic hormone secretion?

a. Furosemide
b. Hydrochlorothiazide
c. Spironolactone
d. Demeclocycline

Answer
Answer is 'd' i.e Demeclocycline.
Demeclocycline produces a type of unresponsiveness to the ADH.
probably by inhibiting the formation and action of cyclic AMP(second messenger of ADH) in the renal tubule.


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